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    Accelerator-based HPC for Genomic computational building blocks

    DIETI Contact person / Partner: Alessandro Cilardo

    Abstract

    Over the past two decades, genomic has paved the way for new breakthroughs in biology and medicine. The ability to effectively handle and process genomic information, e.g. for activities like analysing and aligning DNA and protein sequences as well as generating 3D models of protein structures, is by all means crucial. The activity is focused on understanding the computational implications of next-generation sequencing approaches as well as investigating developments at the algorithm and implementation level matching the opportunities of emerging high-performance computing (HPC) accelerator-based technologies.

    Objective

    The main objectives of the activity will include:

    • studying the computational building blocks in current genomic applications;
    • investigating efficient implementation approaches based on emerging accelerator-based architectures, including GPU and FPGA devices;
    • demonstrating the proposed approaches on next-generation HPC platforms, including large scale HPC facilities and/or small-scale innovative prototypes.

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    Available

    Can be assigned to one doctoral student of cycle XXXVI 

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